GnRH antagonist ganirelix prevents premature luteinization in IUI cycles: rationale for its use

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Treatment with the GnRH antagonist ganirelix prevents premature LH rises and luteinization in stimulated intrauterine insemination: results of a double-blind, placebo-controlled, multicentre trial.

BACKGROUND This study was designed to assess whether the use of ganirelix in women undergoing stimulated IUI could prevent the occurrence of premature LH rises and luteinization (LH+progesterone rises). METHODS Women of infertile couples, diagnosed with unexplained or male factor infertility, were randomized to receive either ganirelix (n=103) or placebo (n=100) in a double-blind design. All ...

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Study of Positive and Negative Consequences of Using GnRH Antagonist in Intrauterine Insemination Cycles

Background To assess the usefulness of premature luteinization hormone (LH) surge prevention in an intrauterine insemination (IUI) cycle by GnRH antagonist administration MaterialsAndMethods Sixty patients with unexplained or mild male infertility or minimal to mild endometriosis were enrolled in this prospective randomized controlled trial. There were twenty patients in group A (with GnRH anta...

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Antagonist use in intrauterine insemination (IUI) cycles İntrauterin inseminasyon sikluslarında antagonist kullanımı

Özet Intrauterine insemination is the first method of treatment for many causes of infertility, mainly unexplained infertility,male subfertility, and ovulatory dysfunction.Despite its popularity, the effectiveness of IUI treatment is not consistent,and the role of IUI treatment in practice protocols has not been clarified.The success of IUI depends on a number of parameters linked both to the p...

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Estradiol valerate pretreatment in GnRH-antagonist cycles.

We read with great interest the Commentary of Griesinger and Kolibianakis (2012) about scheduling oocyte retrieval in GnRH antagonist cycles. Recently, the results of a randomized trial by our group were published, reporting a significant decrease in oocyte retrieval during weekend days following administration of estradiol valerate in the luteal phase of the cycle prior to the stimulated cycle...

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GnRH agonist and GnRH antagonist in intracytoplasmic injection cycles.

The long agonistic protocol for controlled ovarian hyperstimulation (COH) is effective and used most often, thus is considered the gold standard. Therefore any new regimen has to be compared in its results with those obtained with the long protocol. This report compares the efficacy of GnRH agonist and antagonist in a retrospective study of IVF/ICSI carried out in a tertiary teaching hospital f...

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ژورنال

عنوان ژورنال: Reproductive BioMedicine Online

سال: 2009

ISSN: 1472-6483

DOI: 10.1016/s1472-6483(10)60066-1